There was a time when 800x600 screen resolution was very popular with web designers.  However, over the years with increased use of high resolution monitors the number of people using 800x600 screen resolutions has gradually fallen. Now this screen resolution is generally used by the people who have visual impairment and screen resolution of 800x600 on their monitors helps them in reading text on computer screen. According to Market share, the global share of 800x600 screen resolution is a little over 4%. The most popular resolution is the 1024 x 768. So you can always have a liquid web design template where the width of the column that contains text is fixed.